Emil Nashi, MD, MSc, PhD
Research Institute of the McGill University Health Centre
Associate Member Infection and immunity
McGill University Health Centre (MUHC)
Department of Medicine
My research focuses on studying autoimmune disease, in particular lupus. We are currently focusing on B cells, which are cells that play an important role in lupus. In particular, we are currently studying how B cells respond to their environment and comparing this between lupus patients and people without autoimmune disease.
- BCR signaling
- translational research
B cells, signaling, genetics, autoimmune disease, lupus.
Nashi E, Rauch J, Goedert JJ, Pineau CA and Bernatsky S., CXC chemokine receptor type 4 in systemic lupus., J Autoimmun Cell Response., Volume 1, Issue 2, 1-2 (June 2014)
Manjarrez-Orduño N , Marasco E , Chung SA , Katz MS , Kiridly JF , Simpfendorfer KR , Freudenberg J , Ballard DH , Nashi E , Hopkins TJ , Cunninghame Graham DS , Lee AT , Coenen MJ , Franke B , Swinkels DW , Graham RR , Kimberly RP , Gaffney PM , Vyse TJ , Behrens TW , Criswell LA , Diamond B , Gregersen PK, CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation., Nature genetics, Volume 44, Issue 11 (November 2012)
Nashi E , Wang Y , Diamond B, The role of B cells in lupus pathogenesis., The international journal of biochemistry & cell biology, Volume 42, Issue 4 (April 2010)
Grimaldi C , Nashi E , Venkatesh J , Diamond B, B cell hyporesponsiveness and autoimmunity: a new paradigm., Advances in experimental medicine and biology, Volume 596 (January 2007)
Nashi E , Banerjee D , Crelinsten G, Hypoparathyroidism in systemic lupus erythematosus., Lupus, Volume 14, Issue 2 (January 2005)